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Introduction: Dentists perform a variety of surgical procedures frequently requiring the need for a hemostatic agent, in cases where oral anticoagulants are used.Most cases of postoperative bleeding are easily treated with local measures such as packing with a haemostatic dressing, suturing and pressure are satisfactory.
Objectives: the aim of the work is to evaluate the efficacy of Collaplug® in minimizing postoperative bleeding and pain following tooth extraction in patients under oral anticoagulant therapy.
Materials and methods: A prospective study was conducted on a total of 40 adult patients treated with oral anticoagulant therapy, who are in need for tooth extraction. Patients were divided equally into two groups, each group consisting of 20 patients.Group A (Study group): the extraction of the tooth was followed by the application of Collaplug® prior to suturing of the socket.Group B (Control group): the extraction of the tooth was followed by suturing only.
Results: A total of 40 patients 21 female(52%) and 19(48%) male, aged between 30 and 60 years (mean =45) were included in the present study. All patients underwent simple tooth extraction while undergoing oral anticoagulants treatment, in study group: there is clinical sinificane after 2hrs of extraction between both groups MCp=<0.001* in study group:all 20 cases showed mild bleeding grade 2 (G2) according to WHO scale, after application of Collaplug® 2 cases only showed bleeding grade 1 (G1)and the rest of cases showed grade 0 G (0) no bleeding, patients showed no bleeding grade 0(G0) according to the WHO scale within the first 6 hours and post operative pain was reduced in study group,all patients of study and control groups had their international normalized ratio(INR)<3 within the therapeutic range.
In the present study we have shown that Collaplug® is an effective local haemostatic material following minor oral surgery in patients whom are under oral anticoagulant therapy,also shows acceleration of soft tissue healing and postoperative pain reduction in patients, a close follow-up and monitoring of patients taking warfarin is mandatory after dental extraction.